日本熟妇人妻中出,玩两个丰满老熟女久久网,亚洲av无码一区二区三区观看,曰本真人做爰无遮挡

歡迎來到江蘇齊氏生物科技有限公司網(wǎng)站!
咨詢熱線

19805114880

當(dāng)前位置:首頁  >  技術(shù)文章  >  ERα系列抗體的應(yīng)用研究(雌激素受體研究值得關(guān)注)

ERα系列抗體的應(yīng)用研究(雌激素受體研究值得關(guān)注)

更新時間:2021-06-10  |  點擊率:1924
引言:  雌激素受體alpha (ERα)分布于子宮、睪丸、腦下垂體、腎、附睪、腎上腺、乳腺等組織,其作為核轉(zhuǎn)錄因子參與人體多種復(fù)雜生理過程的調(diào)節(jié)。ERα受體表達和調(diào)節(jié)的研究對多種疾病的預(yù)防和治療有積極意義,例如癌癥、代謝性疾病、心血管疾病、神經(jīng)退行性疾病、炎癥和骨質(zhì)疏松癥等[1]。蛋白表達在ERα受體表達調(diào)節(jié)研究中占有重要地位,而ERα抗體則是ERα受體表達的重要研究工具。 

 

 

       雌激素受體alpha (ERα)分布于子宮、睪丸、腦下垂體、腎、附睪、腎上腺、乳腺、骨等組織,其作為核轉(zhuǎn)錄因子參與人體多種復(fù)雜生理過程的調(diào)節(jié)。ERα受體表達和調(diào)節(jié)的研究對多種疾病的預(yù)防和治療有積極意義,例如癌癥、代謝性疾病、心血管疾病、神經(jīng)退行性疾病、炎癥和骨質(zhì)疏松癥等[1]。蛋白表達在ERα受體表達調(diào)節(jié)研究中占有重要地位,而ERα抗體則是ERα受體表達的重要研究工具。 

      ERα受體包括多個功能結(jié)構(gòu)域,不同的轉(zhuǎn)錄剪接產(chǎn)生不同的轉(zhuǎn)錄異構(gòu)體[2],主要包括ERα36和ERα46。由于與疾病的密切相關(guān)性,ERα36、ERα46和野生型ERα (ERα66)一起成為ER家族研究熱點,相應(yīng)的抗體也成為對應(yīng)的研究工具。美國CHI Scientific提供的 ERα系列(ER-α36, ER-α46 & 66, ER-α36)抗體靈敏度高,特異性強,自面試以來,引用該系列產(chǎn)品的文獻達上百篇。尤其是Anti-hER-α36抗體,為美國CHI Scientific生產(chǎn)銷售的產(chǎn)品,為廣大中外科研學(xué)者研究ERα36相關(guān)疾病提供強有力支撐。


論文截圖:
 

Anti-hER-α36

The antibody was raised against a synthetic peptide antigen corresponding to the unique C-terminal 20 amino acids of hER-α36. The specificity of the antibody was tested in hER-α36 expression vector transfected HEK293 cells that do not express endogenous hER-α. Immunofluorescence was used to demonstrate immunoreactive signals only in transfectants with the hER-α36-expressing vectors but not in transfectants harboring an empty expression vector. This rabbit polyclonal anti-hER-α36 antibody is supplied in affinity-purified form.

(引用SCI論文截圖)

Anti-hER-α46 & ER-α66:

The antibody was raised against a synthetic peptide antigen corresponding to the unique C-terminal 18 amino acids of hER-α66. The specificity of the antibody was tested in hER-α46 and hER-α66 expression cells, MCF-7 Cells and breast carcinoma tissues. This rabbit polyclonal anti-hER-α46 & hER-α66 antibody is supplied in affinity-purified form.

(引用SCI論文截圖)

Anti-hER-α66

 The antibody was raised against a synthetic peptide antigen corresponding to the unique C-terminal 18 amino acids of hER-α66. The specificity of the antibody was tested in hER-α66 expression cells, MCF-7 Cells and breast carcinoma tissues. This rabbit polyclonal anti-hER-α66 antibody is supplied in affinity-purified form.

(引用SCI論文截圖)

規(guī)格型號:

 

更多引用:

1.Estrogen signaling and estrogen receptors as prognostic indicators in laryngeal cancerA Verma, N Schwartz, DJ Cohen, BD Boyan… - Steroids, 2019 - Elsevier 

2.24R, 25-dihydroxyvitamin D3 modulates tumorigenicity in breast cancer in an estrogen receptor-dependent mannerA Verma, Z Schwartz, BD Boyan - Steroids, 2019 - Elsevier 

3.Effect of 17β-estradiol on estrogen receptor negative breast cancer cells in an osteolytic mouse modelDJ Cohen, V Patel, A Verma, BD Boyan, Z Schwartz - Steroids, 2019 - Elsevier 

 

4.Estradiol receptor profile and estrogen responsiveness in laryngeal cancer and clinical outcomesN Schwartz, A Verma, C Muktipaty, C Bivens… - Steroids, 2019 - Elsevier

 

5.Estrogen receptor-alpha 36 mediates the anti-apoptotic effect of estradiol in triple negative breast cancer cells via a membrane-associated mechanismRA Chaudhri, A Hadadi, KS Lobachev… - … et Biophysica Acta (BBA …, 2014 - Elsevier 

6.Membrane estrogen signaling enhances tumorigenesis and metastatic potential of breast cancer cells viaestrogen receptor-α36 (ERα36)RA Chaudhri, R Olivares-Navarrete, N Cuenca… - Journal of Biological …, 2012 - ASBMB

 

迈开腿让我看看你的草莓| 闺蜜撕开的奶罩猛吸我的奶| japanesehd熟女熟妇| 地下女RAPPER胖女| yy视频在线观看| 亚洲av无码专区首页| 宝贝腿再张大点就能吃到扇贝了| 最新av偷拍av偷窥av网站| 女性自慰网站免费观看| 亚洲av无码99久久久国精| 亚洲综合小说另类图片久久| chinese熟女老太hd| 邻居的丰满人妻hd学生| 中文字幕人妻丝袜乱一区三区| 无码熟妇av人妻又粗又大| 久久久久久精品免费免费WEI | 亚洲男同志gay 片可播放| 爆乳熟妇一区二区三区霸乳| 少妇被又大又粗又爽毛片欧美| 国产又黄又猛又粗又爽的a片小说| 国产av一区二区三区传媒| 好猛好深好爽喷水无码视频| 女邻居丰满的奶水在线观看| 小少爷撅着屁股挨C双龙| 日日av夜夜添久久奶无码| 色-情-伦-理一区二区三区| 欧美vivodeshd| 国产av躁一二三区免费播放| 我和丰满岳疯狂做爰| 色婷婷亚洲婷婷七月中文字幕| 国产伦精品一区二区三区免费| 欧美zc00o人与善交| 黑人巨大JEEP日本人| 老熟妇仑乱视频一区二区| 欧美老熟妇欲乱高清视频| 精品欧美一区二区三区久久久| 欧美在线观看| 色婷婷久久综合中文久久蜜桃AV| 锕锕锕锕锕锕~好深啊app下载 | 久久亚洲av成人无码国产电影| 国产在线拍揄自揄拍免费下载|